Abstract Background To evaluate the impact of implementation of 2019 European respiratory distress syndrome (RDS) guidelines on the incidence of bronchopulmonary dysplasia (BPD).Method We retrospectively collected the clinical data of very preterm infants (VPIs) born before 32 gestational weeks from January 1st 2018 to December 31st 2021.VPIs were
Selfish genetic elements can promote their transmission at the expense of individual survival, creating conflict between the element and the rest of the genome.Recently, a large number of toxin-antidote (TA) post-segregation distorters have been identified in non-obligate outcrossing nematodes.Their origin and the evolutionary forces that keep Grap
The development of anti-virulence drug therapy against Acinetobacter baumannii infections would provide an alternative to traditional antibacterial therapy that are increasingly failing.Here, we demonstrate that the OmpR transcriptional regulator plays a pivotal role in the pathogenesis of diverse A.baumannii clinical strains in multiple murine and
The AB-type protein toxin from Pasteurella multocida (PMT) contains a functionally important disulfide bond within its catalytic domain, which must be cleaved in the host cell cytosol to render the catalytic domain of PMT into its active conformation.Here, we found that the reductive potential of the cytosol of target cells, and more specifically,
Crop consumptive water use is recognized as a key element to understand regional water management performance.This study documents an attempt to apply a regional evapotranspiration model (SEBAL) and crop information for assessment of regional crop (summer maize and winter wheat) actual evapotranspiration (ETa) in Huang-Huai-Hai (3H) Plain, China.Th